4-FLUORO-2-METHOXYBENZOIC ACID

4-FLUORO-2-METHOXYBENZOIC ACID - Names and Identifiers

Name	4-Fluoro-2-methoxybenzoic acid
Synonyms	Jrd-1709 BUTTPARK 511-27 RARECHEM AL BE 1023 4-Fluoro-o-anisic Acid 4-FLUORO-2-METHOXYBENZOIC ACID 4-Fluoro-2-methoxybenzoic acid 2-Methoxy-4-Fluorobenzoic Acid 2-METHOXY-4-FLUOROBENZOIC ACID 2-Carboxy-5-fluoroanisole, 4-Fluoro-o-anisic acid 4-Fluoro-2-Methoxybenzoic Acid 2-Methoxy-4-Fluorobenzoic Acid
CAS	395-82-4

4-FLUORO-2-METHOXYBENZOIC ACID - Physico-chemical Properties

Molecular Formula	C8H7FO3
Molar Mass	170.14
Density	1.307±0.06 g/cm3(Predicted)
Melting Point	134 °C
Boling Point	93 °C(Press: 10 Torr)
pKa	4.03±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00673010

4-FLUORO-2-METHOXYBENZOIC ACID - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes.
HS Code	29163990
Hazard Note	Irritant

4-FLUORO-2-METHOXYBENZOIC ACID - Introduction

Acid (acid) is an organic compound with the chemical formula C8H7FO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a white crystalline solid.
-Melting point: about 150-152 ℃.
-Solubility: In common organic solvents, such as ethanol and dimethylformamide, the solubility is better.

Use:
-14-acid is an important organic synthesis intermediate, commonly used in the preparation of drugs, pesticides and dyes and other compounds.
-Because of its specific chemical structure and properties, it can also be used as a building block for heterocyclic compounds.

Preparation Method:
The preparation of acid can be carried out by the following steps:
1. First, 2-methoxybenzoic acid and cuprous fluoride (CuF) are reacted under the catalysis of copper (Cu).
2. When the reaction proceeds, the introduction of fluorine atoms can be realized due to the Cu catalyst produced by the decomposition of CuF and 2-methoxybenzoic acid.
3. Next, through a hydrolysis reaction, the resulting reactant is obtained as acid.

Safety Information:
-must acid is generally considered to have low toxicity under normal use conditions.
-However, as an organic compound, it may cause irritation and sensitive reactions to the human body, so safety measures need to be taken when handling it.
-It is recommended to operate in a well-ventilated place and wear appropriate protective equipment, such as gloves and goggles.
-In case of skin contact or inhalation, rinse immediately with plenty of water and seek medical assistance.

Last Update：2024-04-09 21:04:16